Natural products with anti-obesity effects and different mechanisms of action. Toxicol Appl Pharmacol ; Weight-loss products can contain dozens of ingredients, and some contain more than 90 [ 11 ]. But do weight-loss pills and products lighten anything but your wallet? Get updates. Effects of – -hydroxycitric acid on appetitive variables. At higher doses, it can cause nausea, vomiting, rapid heartbeat, and seizures. However, many of the products with these effects contain multiple herbal ingredients, and the role of bitter orange in these adverse effects cannot be isolated. When a dietary supplement is marketed as “clinically proven” to cause weight loss, there should be some type of clinical evidence to support it.
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